GW-1516 was created by Glaxo Smith and Ligand Pharmaceuticals in 1992.
Cardarine (GW-1516) is hands down the best compound out there to increase your physical performance. Not only does it give you an insane endurance boost, but it also has great fat burning properties. There is a reason why so many top athletes choose to use Cardarine.
To give you an example of the success obtainable with Cardarine is the well-known case of Elena Lashmanova, who tested positive for Cardarine after breaking the 20km race walk world record. Because cardarine was abused by various athletes in different sports, the WADA chose to ban the compound in 2009. Overall Cardarine is an excellent and powerful compound to use.
In mice, the GW-1516 combined with 4 weeks of regular racing increased race time by 68% and stroke distance by 70%, and doubled overall muscular endurance. In rodents, GW-1516 plus exercise has increased mitochondrial growth in muscle by ~ 50%, allowing muscles to generate more power without fatigue. It has also decreased fat while preserving muscle. GW-1516 could be a powerful way to improve performance and lose fat while maintaining muscle.
You can read alot online about GW-1516 causing cancer, which is not quite true. Often these people back up the claim by reffering to a study done on rodents which developed cancer during clinical trials.
What they are leaving out is that the rats were given much higher doses than the suggested dose of 10-20mg a day. To put it in perspective, the rats were given 10mg/kg during clinical trial. Which for a 75kg male would equal 750mg of Cardarine a day. This means that they recieved 37 and a half times the suggested dose of 20mg a day.
There are alot of substances that can cause harm when you take 37 and a half times the recommended dose.