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Ibutamoren mk-677 is a selective silent modulator of growth hormone receptors (SmoR). It is thought to increase growth hormone secretion by increasing the number of Growth hormone receptors on the surface of the cells that produce the hormone.
MK-677 may also increase the half-life of growth hormone, allowing it to stay active in the body longer. Reducing the time between each pulse of the hormone reduces the amount of growth hormone required to reach the desired effect. This drug may be useful for muscle growth, fat loss, and the treatment of certain types of dwarfism.
RAD-140, also known as Testolone, is a type of selective androgen receptor modulator (SARM). This means that it has an androgenic effect on muscle tissue while having minimal effects on other tissues in the body. SARMs are particularly interesting to researchers because they selectively target muscle and bone tissues, with little effect on other organs like the prostate.
The chemical structure of RAD-140 is quite different from steroid hormones like testosterone. As a result, the pathways that convert testosterone into other hormones (like estrogen) cannot act on Testolone [1]. This unique structure gives RAD-140 some potential advantages over other androgenic compounds.
In addition to its muscle-building properties, some evidence suggests that RAD-140 may have neuroprotective effects. A study in rats found that RAD-140 could activate receptors in injured regions of the brain, increasing MAPK activity and protecting neurons from damage [5]. While further research is needed to confirm these effects in humans, this suggests that RAD-140 may have potential therapeutic uses beyond its muscle-building properties.
Overall, RAD-140 is a promising compound for bodybuilders and researchers alike. Its unique structure and selective targeting make it a potentially safer and more effective alternative to traditional androgenic compounds.
Increasing growth hormones means that muscle cells can recover a lot faster. So, your muscle needs less time to go back to the gym or on the field for a hardcore session. Muscles also feel sore for a much shorter period.
Since MK-677 helps your muscle recover faster, you will build a lot more muscle mass in a shorter period! Muscles are not built in the gym but during recovery. Better recovery better gains.
An increase in HGH production means that all cells are recovering faster. Not only the muscle but also the joints, tendons, and ligaments. Ibutamoren also creates a little bit of water retention, especially in joints which is awesome for joint health!
One of the key factors of aging is the fact that past 30 years old the level of growth hormone decline pretty fast. That’s why many athletes and celebrities take HGH to stay younger and healthier longer. With MK-677 it’s now easier than ever to get the same results!
Cells need energy to recover and regenerate, in the human body, energy is calories. Having higher levels of HGH and recovering faster mean that you burn a lot more calories on a daily basis. This leads to burning fat! Ibutamoren also acts directly on fat cells to lose fat faster!
Ibutamoren improves sleep quality providing you with a longer REM sleep cycle and shorter sleep latency. MK-677 also decreases LDL, which helps cardiovascular health.2
Being more anabolic also means that you are more likely to retain muscle mass as you are consuming more calories than your body needs to maintain its current weight. High-protein foods are anabolic because they take longer to digest, and thus you are less likely to overeat because of their satiating effect.
Androgens play an important role in protecting the brain. Moreover, they can reduce the risk of developing Parkinson’s disease. Androgens also have an anti-inflammatory effect on the brain. They can decrease the activity of microglia, which are macrophage cells that cause inflammation in the brain.
By reducing the activity of these cells, androgens can improve sleep quality and decrease stress. Furthermore, by increasing the level of serotonin and dopamine, androgens can improve the mood.[5].